Description

2-[3,4-Dihydro-2(1H)-Isoquinolinyl]-5-Methylaniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydroisoquinoline-aniline hybrid structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create complex heterocyclic compounds and fine chemicals.
• Agrochemical Research: Investigated as an intermediate for developing novel crop protection agents and pesticides.
• Academic & Industrial R&D: Serves as a standard or reference material in laboratory-scale research and process development.

Basic Information

Product Name	2-[3,4-Dihydro-2(1H)-Isoquinolinyl]-5-Methylaniline
CAS No.	1097786-11-2
Molecular Formula	C₁₆H₁₈N₂
Molecular Weight	238.33 g/mol
Synonyms	5-Methyl-2-(1,2,3,4-tetrahydroisoquinolin-2-yl)aniline; 2-(5-Methyl-2-aminophenyl)-1,2,3,4-tetrahydroisoquinoline; 2-(5-Methylphenylamino)-1,2,3,4-tetrahydroisoquinoline; 2-(5-Methylanilino)-1,2,3,4-tetrahydroisoquinoline; 2-Amino-4-methylphenyl tetrahydroisoquinoline; Tetrahydroisoquinoline aniline derivative; 1097786-11-2
EINECS	Contact for details

Quality Control

Our 2-[3,4-Dihydro-2(1H)-Isoquinolinyl]-5-Methylaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications, and our quality protocols are designed to meet the stringent requirements of global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.