Description

2-(2,3-Dihydro-1H-Indol-1-Yl)-5-Methylphenylamine is a specialized aromatic amine derivative featuring an indoline moiety, serving as a high-value intermediate in advanced organic synthesis. Its molecular architecture makes it a critical building block for constructing complex heterocyclic systems with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical developers for creating novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in developing advanced crop protection agents and herbicides due to its bioactive heterocyclic core.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers, dyes, and organic electronic materials.
• Chemical Synthesis: A versatile building block for constructing complex indole- and aniline-based libraries in medicinal and combinatorial chemistry.
• Academic & Industrial R&D: Employed in fundamental research to study reaction mechanisms and develop new synthetic methodologies.

Basic Information

Product Name	2-(2,3-Dihydro-1H-Indol-1-Yl)-5-Methylphenylamine
CAS No.	1097786-03-2
Molecular Formula	C15H16N2
Molecular Weight	224.30 g/mol
Synonyms	5-Methyl-2-(2,3-dihydro-1H-indol-1-yl)aniline; 1-(2-Amino-4-methylphenyl)-2,3-dihydro-1H-indole; 2-(Indolin-1-yl)-5-methylaniline; N-(5-Methyl-2-aminophenyl)indoline; 2-Amino-4-methyl-N-indolinylbenzene; 1097786-03-2; 2-(2,3-Dihydro-1H-indol-1-yl)-5-methylbenzenamine
EINECS	Contact for details

Quality Control

Every batch of 2-(2,3-Dihydro-1H-Indol-1-Yl)-5-Methylphenylamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.