Description

(1,2,3,4-Tetrahydro-Isoquinolin-6-Yl)-Methanol (Wx604274) is a high-purity, versatile heterocyclic building block and chiral intermediate. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of complex molecules with potential biological activity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the isoquinoline scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic and Contract Research: Essential reagent for medicinal chemistry programs and methodological studies in universities and CROs (Contract Research Organizations).
• Chemical Biology Probe Development: Used to create molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	(1,2,3,4-Tetrahydro-Isoquinolin-6-Yl)-Methanol (Wx604274)
CAS No.	1095715-75-5
Molecular Formula	C10H13NO
Molecular Weight	163.22 g/mol
Synonyms	6-(Hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline; (6-Isoquinolinyl)methanol, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydro-6-isoquinolinemethanol; Tetrahydroisoquinoline-6-methanol; WX-604274; Wx604274
EINECS	Contact for details

Quality Control

Our (1,2,3,4-Tetrahydro-Isoquinolin-6-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided with every shipment. We can support development projects with custom purity grades, including research and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Research Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (Available on request)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.