Description

3-(2-Hydroxy-4-Methylphenyl)-n-(6-Methoxy-1,3-Benzothiazol-2-Yl)-1H-Pyrazole-5-Carboxamide is a high-purity, advanced pharmaceutical intermediate belonging to a class of heterocyclic compounds featuring a benzothiazole-pyrazole hybrid structure. This compound matters for its critical role as a key building block in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing next-generation therapeutic agents, leveraging its unique molecular scaffold to create compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated building block in the multi-step synthesis of new chemical entities (NCEs) for drug discovery programs.
• Biochemical Research: Serves as a core scaffold or a derivatization starting point in medicinal chemistry for probing structure-activity relationships (SAR).
• API Development: Utilized in the pilot-scale and commercial-scale production of candidate active pharmaceutical ingredients, especially in oncology and central nervous system (CNS) therapeutic areas.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probe: Used in academic and industrial research to study protein-ligand interactions and cellular signaling mechanisms.

Basic Information

Product Name	3-(2-Hydroxy-4-Methylphenyl)-n-(6-Methoxy-1,3-Benzothiazol-2-Yl)-1H-Pyrazole-5-Carboxamide
CAS No.	1095603-22-7
Molecular Formula	C19H16N4O3S
Molecular Weight	380.42 g/mol
Synonyms	1H-Pyrazole-5-carboxamide, 3-(2-hydroxy-4-methylphenyl)-N-(6-methoxy-2-benzothiazolyl)-; 3-(2-Hydroxy-4-methylphenyl)-N-(6-methoxy-1,3-benzothiazol-2-yl)-1H-pyrazole-5-carboxamide; Benzothiazole-pyrazole carboxamide derivative; 1095603-22-7; N-(6-Methoxy-1,3-benzothiazol-2-yl)-3-(2-hydroxy-4-methylphenyl)-1H-pyrazole-5-carboxamide
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxy-4-Methylphenyl)-n-(6-Methoxy-1,3-Benzothiazol-2-Yl)-1H-Pyrazole-5-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.