Description

2-(7-Methoxy-2-Naphthalenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. This compound is critical for enabling complex organic transformations, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Serves as a crucial building block in the development of new drug candidates, particularly those containing naphthalene and methoxy-substituted aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Biology Probes: Acts as a precursor for creating labeled compounds and probes used in biochemical and medicinal research.
• Catalyst and Ligand Development: Utilized in the preparation of novel organoboron-based catalysts and ligands for asymmetric synthesis.

Basic Information

Product Name	2-(7-Methoxy-2-Naphthalenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane
CAS No.	1094897-81-0
Molecular Formula	C₁₇H₂₁BO₃
Molecular Weight	284.16 g/mol
Synonyms	5,5-Dimethyl-2-(7-methoxynaphthalen-2-yl)-1,3,2-dioxaborinane; 2-(7-Methoxy-2-naphthyl)-5,5-dimethyl-1,3,2-dioxaborinane; 7-Methoxy-2-naphthaleneboronic acid 5,5-dimethyl-1,3,2-dioxaborinane ester; 2-(7-Methoxynaphthalen-2-yl)-5,5-dimethyl-1,3,2-dioxaborinane; 7-Methoxy-2-naphthaleneboronic acid cyclic ester with neopentyl glycol; (7-Methoxynaphthalen-2-yl)boronic acid neopentyl glycol ester; Boronic ester of 7-methoxy-2-naphthaleneboronic acid.
EINECS	Contact for details

Quality Control

Our 2-(7-Methoxy-2-Naphthalenyl)-5,5-Dimethyl-1,3,2-Dioxaborinane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.