Description

Ethyl 3-Amino-5-(3-Chlorophenyl)-Thiophene-2-Carboxylate is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its thiophene and chlorophenyl motifs for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and other functional materials due to its electron-rich thiophene core.
• Chemical Synthesis: Employed in organic chemistry research for constructing complex heterocyclic compounds and in method development (e.g., Suzuki coupling, amidation).
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized dyes and pigments with specific light-absorption properties.

Basic Information

Item	Details
Product Name	Ethyl 3-Amino-5-(3-Chlorophenyl)-Thiophene-2-Carboxylate
CAS No.	1094398-54-5
Molecular Formula	C13H12ClNO2S
Molecular Weight	281.76 g/mol
Synonyms	Ethyl 3-Amino-5-(3-chlorophenyl)thiophene-2-carboxylate; 3-Amino-5-(3-chlorophenyl)thiophene-2-carboxylic acid ethyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-(3-chlorophenyl)-, ethyl ester; Ethyl 3-amino-5-(m-chlorophenyl)thiophene-2-carboxylate; 1094398-54-5; Ethyl α-amino-3'-chloro-2,2'-bithiophene-5-carboxylate (related structure)
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-5-(3-Chlorophenyl)-Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.