Description

Methyl 3-Amino-5-(3-Bromophenyl)Thiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block featuring a bromophenyl substituent and an ester-protected carboxylic acid group. This compound matters for its role as a critical intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and advanced material science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its thiophene and bromophenyl motifs for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Chemical Synthesis: Utilized in Suzuki-Miyaura and other cross-coupling reactions, where the bromine atom acts as a handle for further functionalization.
• Dye & Pigment Industry: Acts as an intermediate for the production of specialized dyes and pigments with unique color properties and stability.

Basic Information

Product Name	Methyl 3-Amino-5-(3-Bromophenyl)Thiophene-2-Carboxylate
CAS No.	1094398-45-4
Molecular Formula	C12H10BrNO2S
Molecular Weight	312.18 g/mol
Synonyms	Methyl 3-amino-5-(3-bromophenyl)thiophene-2-carboxylate; 3-Amino-5-(3-bromophenyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-5-(3-bromophenyl)-, methyl ester; 1094398-45-4; Methyl 3-amino-5-(m-bromophenyl)thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-(3-Bromophenyl)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.