Description

4-Methoxy-1H-Indole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the generation of focused compound libraries.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Peptidomimetic Design: The indole core can be incorporated into peptide analogs to modulate biological activity and stability.

Basic Information

Item	Detail
Product Name	4-Methoxy-1H-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1093759-59-1
Molecular Formula	C15H19NO3
Molecular Weight	261.32 g/mol
Synonyms	1-Boc-4-methoxyindole; tert-Butyl 4-methoxy-1H-indole-1-carboxylate; 4-Methoxyindole-1-carboxylic Acid tert-Butyl Ester; 1-(tert-Butoxycarbonyl)-4-methoxy-1H-indole; 4-Methoxy-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 1-N-Boc-4-methoxyindole; 4-Methoxy-1-indolecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-Methoxy-1H-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing all quality parameters are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.