Description

1-[Tris(1-Methylethyl)Silyl]-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, organosilicon-protected pyrrolopyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its primary value lies in enabling complex molecular construction, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality building blocks for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products, leveraging its heterocyclic core structure.
• Material Science: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its fused ring system.
• Chemical Synthesis: Acts as a versatile protected intermediate in multi-step organic synthesis, facilitating the introduction of the pyrrolopyridine moiety under mild conditions.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical spaces.

Basic Information

Product Name	1-[Tris(1-Methylethyl)Silyl]-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1093759-49-9
Molecular Formula	C17H28N2Si
Molecular Weight	288.51 g/mol
Synonyms	1-(Triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 1-[tris(1-methylethyl)silyl]-; TIPS-Pyrrolopyridine; 1-Triisopropylsilyl-7-azaindole; 1-TIPS-7-azaindole; 1-(Triisopropylsilyl)-7-azaindole; 1-Triisopropylsilyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-[Tris(1-Methylethyl)Silyl]-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.