Description

1-Chloro-6-Methylisoquinolin-5-Amine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific structural motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysts, and photoactive compounds due to its conjugated aromatic system.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways and enzyme functions.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and exploration of new chemical spaces.

Basic Information

Product Name	1-Chloro-6-Methylisoquinolin-5-Amine
CAS No.	1093101-44-0
Molecular Formula	C10H9ClN2
Molecular Weight	192.65 g/mol
Synonyms	5-Amino-1-chloro-6-methylisoquinoline; 1-Chloro-6-methyl-5-isoquinolinamine; 6-Methyl-1-chloroisoquinolin-5-amine; 1093101-44-0; 1-Chloro-6-methylisoquinolin-5-ylamine
EINECS	Contact for details

Quality Control

Our 1-Chloro-6-Methylisoquinolin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.