Description

2-Methyl-2,3-Dihydro-1H-Spiro[Cyclopropane-1,4-Isoquinolin]-7-Amine CAS NO 1092794-11-0 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic isoquinoline scaffold. This compound is of significant value for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers focused on creating innovative therapeutic agents, particularly in the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex, three-dimensional spirocyclic structure.
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study biological mechanisms and protein interactions.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and methodology development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and scale-up projects.

Basic Information

Product Name	2-Methyl-2,3-Dihydro-1H-Spiro[Cyclopropane-1,4-Isoquinolin]-7-Amine
CAS No.	1092794-11-0
Molecular Formula	C12H14N2
Molecular Weight	186.25 g/mol
Synonyms	7-Amino-2-methyl-2,3-dihydro-1H-spiro[cyclopropane-1,4'-isoquinoline]; 2-Methyl-2,3-dihydrospiro[cyclopropane-1,4'-isoquinoline]-7-amine; 2-Methyl-2,3-dihydro-1H-spiro[cyclopropane-1,4-isoquinolin]-7-amine; Spiro[cyclopropane-1,4'-isoquinoline]-7-amine, 2-methyl-2,3-dihydro-; 1092794-11-0; 2-Methyl-2,3-dihydro-1H-spiro[cyclopropane-1,4-isoquinoline]-7-ylamine
EINECS	Contact for details

Quality Control

Our 2-Methyl-2,3-Dihydro-1H-Spiro[Cyclopropane-1,4-Isoquinolin]-7-Amine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.