Description

4-{[2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Carbonyl}Morpholine is a sophisticated boronic ester derivative that serves as a key synthetic intermediate in modern organic chemistry. Its core value lies in enabling the construction of complex molecular architectures through reliable cross-coupling reactions, offering chemists a stable and reactive handle for carbon-boron bond formation. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders, inflammation, and oncology.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable boronic ester reagent for forming carbon-carbon bonds between aromatic rings, a fundamental step in creating complex organic molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-morpholine motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology & Probe Development: Utilized as a precursor for creating molecular probes and tags used in bio-conjugation and cellular imaging studies.
• Process Chemistry & Scale-Up: Provides a reliable and scalable intermediate for pilot plant and commercial-scale manufacturing of fine chemicals.

Basic Information

Product Name	4-{[2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Carbonyl}Morpholine
CAS No.	1092564-35-6
Molecular Formula	C18H26BNO5
Molecular Weight	347.22 g/mol
Synonyms	(4-(2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)morpholine; 2-Methoxy-4-(morpholine-4-carbonyl)phenylboronic acid pinacol ester; 4-(2-Methoxy-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl)morpholine; Morpholine, 4-[[2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbonyl]-; 1092564-35-6; AKOS025310065; A1-00896
EINECS	Contact for details

Quality Control

Every batch of 4-{[2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Carbonyl}Morpholine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.