Description

4-(Chloromethyl)-2-Nitrothiophene is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its reactive chloromethyl and nitro functional groups. It is primarily sought after by research institutions and industrial R&D departments for the synthesis of novel thiophene-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a precursor for functional polymers, organic semiconductors, and conductive materials due to the electron-rich thiophene core.
• Chemical Synthesis: A versatile reagent for further functionalization, including nucleophilic substitution of the chloromethyl group and reduction of the nitro group.
• Dye and Pigment Intermediate: Used in the development of specialized dyes and pigments where the nitro-thiophene structure imparts specific color and stability properties.

Basic Information

Product Name	4-(Chloromethyl)-2-Nitrothiophene
CAS No.	1092561-29-9
Molecular Formula	C5H4ClNO2S
Molecular Weight	177.61 g/mol
Synonyms	2-Nitro-4-(chloromethyl)thiophene; 4-Chloromethyl-2-nitrothiophene; 2-Nitrothiophene-4-methylene chloride; (2-Nitro-4-thienyl)methyl chloride; 4-(Chloromethyl)-2-nitro-thiophene; 2-Nitro-4-thiophenemethyl chloride
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)-2-Nitrothiophene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, identity confirmation by FT-IR and NMR, and impurity profiling. A Certificate of Analysis (COA) is supplied with every batch to guarantee compliance with your technical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.