Description

Moxifloxacin D3 is a deuterium-labeled analog of the broad-spectrum fluoroquinolone antibiotic moxifloxacin, specifically designed for use as an internal standard in analytical chemistry. This high-purity stable isotope-labeled compound is essential for ensuring the accuracy and reliability of quantitative analyses, particularly in pharmacokinetic and bioequivalence studies. It is a critical tool for pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities that require precise and reproducible results in method development and validation.

Application

• Internal Standard for LC-MS/MS Analysis: Primary application as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the accurate measurement of moxifloxacin in biological matrices.
• Pharmacokinetic and Metabolism Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Bioanalytical Method Development & Validation: Used to develop, optimize, and validate robust analytical methods compliant with FDA, EMA, and ICH guidelines.
• Drug Impurity Profiling and Degradation Studies: Assists in the identification and quantification of related substances and degradation products in drug substances and products.
• Quality Control in Pharmaceutical Manufacturing: Serves as a critical reference material for in-process testing and final product release to ensure batch consistency and purity.
• Forensic and Doping Control Analysis: Applied in specialized testing laboratories for the definitive identification and quantification of moxifloxacin.

Basic Information

Product Name	Moxifloxacin D3
CAS No.	1092356-42-7
Molecular Formula	C21H21D3FN3O4
Molecular Weight	404.43 g/mol
Synonyms	Moxifloxacin-d3; 1-Cyclopropyl-7-[(1S,6S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid-d3; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic Acid-d3; Avelox-d3; BAY 12-8039-d3; Moxifloxacin (methyl-d3); Deuterated Moxifloxacin
EINECS	Contact for details

Quality Control

Our Moxifloxacin D3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry for isotopic enrichment verification and HPLC for chemical and isotopic purity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, ensuring traceability and compliance with the stringent requirements of analytical reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (deuterium content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.