Description

3-(6-Chloro-1H-Indol-3-Yl)-3-Oxopropanenitrile is a high-purity, specialized chemical building block featuring a chlorinated indole core. This compound is valued for its role as a key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Organic Synthesis: Serves as a versatile precursor for creating more complex indole derivatives and β-ketonitriles in academic and industrial laboratories.
• Material Science: Potential intermediate in the synthesis of organic semiconductors and photoactive materials due to its conjugated system.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a probe for studying biological pathways involving indole-based recognition.

Basic Information

Product Name	3-(6-Chloro-1H-Indol-3-Yl)-3-Oxopropanenitrile
CAS No.	1092299-42-7
Molecular Formula	C11H7ClN2O
Molecular Weight	218.64 g/mol
Synonyms	3-(6-Chloro-1H-indol-3-yl)-3-oxopropanenitrile; 6-Chloro-3-cyanoacetylindole; 3-(6-Chloroindol-3-yl)-3-oxopropanenitrile; 2-(6-Chloro-1H-indol-3-yl)-2-oxoacetonitrile; 6-Chloro-1H-indole-3-acetonitrile, β-oxo-; (6-Chloro-1H-indol-3-yl)(cyano)methanone; β-Oxo-6-chloro-1H-indole-3-propionitrile
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 3-(6-Chloro-1H-Indol-3-Yl)-3-Oxopropanenitrile is analyzed using advanced techniques like HPLC, NMR, and MS to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.