Description

3-Iodo-1H-Indole-5-Carbonitrile is a versatile and high-value halogenated indole derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an iodine substituent and a nitrile group, makes it an essential intermediate for constructing complex heterocyclic compounds. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical pathway studies.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings to create complex biaryl structures.
• Functional Dye Synthesis: Intermediate for producing specialized indole-based dyes and pigments with specific optical properties.

Basic Information

Item	Detail
Product Name	3-Iodo-1H-Indole-5-Carbonitrile
CAS No.	1092114-59-4
Molecular Formula	C9H5IN2
Molecular Weight	284.05 g/mol
Synonyms	5-Cyano-3-iodo-1H-indole; 3-Iodo-1H-indole-5-carbonitrile; 1H-Indole-5-carbonitrile, 3-iodo-; 3-Iodoindole-5-carbonitrile; 5-CN-3-I-indole
EINECS	Contact for details

Quality Control

Our 3-Iodo-1H-Indole-5-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.