Description

4-[(Thiophen-3-Yl)Carbonyl]Morpholine is a high-purity organic building block featuring a morpholine ring linked to a thiophene carbonyl moiety. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active compounds or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or as protease inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and morpholine heterocycles.
• Material Science Research: Serves as a precursor for organic electronic materials, such as conductive polymers or organic semiconductors, due to its conjugated system.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis or organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	4-[(Thiophen-3-Yl)Carbonyl]Morpholine
CAS No.	1090955-28-4
Molecular Formula	C9H11NO2S
Molecular Weight	197.26 g/mol
Synonyms	Morpholine, 4-[(3-thienyl)carbonyl]-; 4-(Thiophene-3-carbonyl)morpholine; 3-Morpholin-4-yl(3-thienyl)methanone; (3-Thienyl)(morpholino)methanone; 4-(3-Thiophenoyl)morpholine; 4-(3-Thienoyl)morpholine; 4-(Thiophen-3-ylcarbonyl)morpholine
EINECS	Contact for details

Quality Control

Our 4-[(Thiophen-3-Yl)Carbonyl]Morpholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.