Description

3-(4-Bromothiophen-2-Yl)-2-Cyanoprop-2-Enoic Acid is a high-purity, multi-functional organic building block featuring a brominated thiophene core. This compound is valued for its unique molecular architecture, which enables its use as a key intermediate in the synthesis of complex heterocyclic systems and advanced materials. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Acts as a monomer or building block for constructing conjugated polymers and organic semiconductors for use in OLEDs and electronic devices.
• Chemical Research: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive bromine substituent, facilitating the creation of diverse chemical libraries.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for metal-organic frameworks (MOFs) and asymmetric catalysis.

Basic Information

Product Name	3-(4-Bromothiophen-2-Yl)-2-Cyanoprop-2-Enoic Acid
CAS No.	1087780-82-2
Molecular Formula	C8H4BrNO2S
Molecular Weight	258.09 g/mol
Synonyms	2-Cyano-3-(4-bromo-2-thienyl)-2-propenoic Acid; (2E)-2-Cyano-3-(4-bromothiophen-2-yl)prop-2-enoic Acid; 3-(4-Bromothiophen-2-yl)-2-cyanoprop-2-enoic Acid; 4-Bromo-2-thiopheneacrylic acid, α-cyano-; α-Cyano-3-(4-bromothiophen-2-yl)acrylic acid; 1087780-82-2; (E)-2-Cyano-3-(4-bromothiophen-2-yl)acrylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Bromothiophen-2-Yl)-2-Cyanoprop-2-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our standard grade meets research and development requirements, with custom purity grades (e.g., >98%, >99%) available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.