Description

7-Aminomethyl-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester is a protected indole derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its primary value lies in providing a versatile, reactive amine handle while protecting the indole nitrogen, enabling complex multi-step syntheses with high selectivity and yield. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for constructing novel heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides with complex heterocyclic structures.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science Research: Employed in the development of organic semiconductors, photochromic materials, and advanced polymers.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including catalysis and new bond-forming reactions.
• Custom Synthesis & Scale-Up: Supplied for custom manufacturing projects requiring gram to kilogram quantities under cGMP or ISO standards.

Basic Information

Product Name	7-Aminomethyl-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1086392-30-4
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 2,3-dihydro-7-(aminomethyl)-, 1,1-dimethylethyl ester; tert-Butyl 7-(aminomethyl)-2,3-dihydro-1H-indole-1-carboxylate; 7-(Aminomethyl)-2,3-dihydro-1H-indole-1-carboxylic acid tert-butyl ester; Boc-7-aminomethyl-2,3-dihydroindole; 7-Aminomethylindoline-1-carboxylic acid tert-butyl ester; 1-Boc-7-aminomethyl-2,3-dihydroindole; 1086392-30-4
EINECS	Contact for details

Quality Control

Our 7-Aminomethyl-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production facilities adhere to ISO 9001 standards, and we can support development projects requiring material produced under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and reactivity. For long-term storage (>12 months), consider storage under an inert atmosphere (argon or nitrogen).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.