Description

(2,3-Dihydro-1H-Indol-3-Yl)-Carbamic Acid tert-Butyl Ester is a protected indoline derivative that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its primary value lies in providing a reactive amine handle while offering stability under a wide range of reaction conditions, enabling the efficient synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indoline-based drug candidates, including potential central nervous system (CNS) agents and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that incorporate the indoline scaffold for enhanced biological activity.
• Organic Synthesis Reagent: Serves as a protected amine precursor in multi-step synthetic routes, including peptide coupling and heterocycle formation.
• Chemical Research & Development: Fundamental material for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, dyes, and functional materials requiring the indoline structure.

Basic Information

Product Name	(2,3-Dihydro-1H-Indol-3-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1086392-28-0
Molecular Formula	C₁₃H₁₈N₂O₂
Molecular Weight	234.29 g/mol
Synonyms	tert-Butyl (2,3-dihydro-1H-indol-3-yl)carbamate; 3-[(tert-Butoxycarbonyl)amino]indoline; N-Boc-3-aminoindoline; Boc-3-Aminoindoline; (2,3-Dihydro-1H-indol-3-yl)carbamic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl (2,3-dihydro-1H-indol-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our (2,3-Dihydro-1H-Indol-3-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.