Description

3-Chloro 1H-Indazole-6-Carboxylic Acid Methyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for medicinal chemistry research and pharmaceutical development, serving as a key intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, and insecticides with potential new modes of action.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for advanced material science and specialty chemical applications.
• Biochemical Tool Compound: Can be utilized to develop probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	3-Chloro 1H-Indazole-6-Carboxylic Acid Methyl Ester
CAS No.	1086391-18-5
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	Methyl 3-chloro-1H-indazole-6-carboxylate; 3-Chloro-1H-indazole-6-carboxylic acid methyl ester; 6-Carbomethoxy-3-chloroindazole; 1H-Indazole-6-carboxylic acid, 3-chloro-, methyl ester; 1086391-18-5; Methyl 3-chloroindazole-6-carboxylate; 3-Chloro-6-(methoxycarbonyl)-1H-indazole
EINECS	Contact for details

Quality Control

Our 3-Chloro 1H-Indazole-6-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.