Description

3-Bromo-1H-Indazol-5-Carbaldehyde is a high-purity, versatile heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its bifunctional reactivity, featuring both a bromo substituent and an aldehyde group, which allows for sequential and site-specific derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for creating advanced organic frameworks, ligands for catalysis, and functional polymers.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for nucleophilic addition to the aldehyde group.
• Bioconjugation & Probe Development: The aldehyde functionality enables its use in labeling and bioconjugation strategies for diagnostic and research applications.

Basic Information

Product Name	3-Bromo-1H-Indazol-5-Carbaldehyde
CAS No.	1086391-08-3
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	5-Formyl-3-bromo-1H-indazole; 3-Bromo-1H-indazole-5-carboxaldehyde; 3-Bromo-5-formyl-1H-indazole; 1H-Indazole-5-carboxaldehyde, 3-bromo-; 3-Bromoindazole-5-carbaldehyde; 1086391-08-3; 3-Bromo-1H-indazol-5-yl-methanal
EINECS	Contact for details

Quality Control

Our 3-Bromo-1H-Indazol-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.