Description

1H-Pyrrolo[2,3-B]Pyridine-4-Carboxamide is a high-purity heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. This specialized intermediate is valued for its unique fused bicyclic structure, which is integral to the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially kinase inhibitors.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic scaffolds with potential biological activity.
• Research & Development (R&D): Essential material for academic and industrial laboratories exploring new chemical entities and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Development: Employed in the synthesis of potential APIs targeting specific disease pathways.
• Biochemical Research: Used as a standard or probe in biochemical assays to study enzyme interactions and cellular processes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-4-Carboxamide
CAS No.	1086390-83-1
Molecular Formula	C8H7N3O
Molecular Weight	161.16 g/mol
Synonyms	4-Carbamoyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-4-carboxylic acid amide; 4-Pyrrolo[2,3-b]pyridinecarboxamide; 7-Azaindole-4-carboxamide; 4-Carbamoyl-7-azaindole; 1H-7-Azaindole-4-carboxamide; 7-Aza-1H-indole-4-carboxamide; 1H-Pyrrolo[2,3-b]pyridine-4-carboxamide
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality standards are designed to meet the rigorous demands of pharmaceutical R&D and can be aligned with cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.