Description

4-Bromo-2-hydroxythiazole is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its functionalized thiazole core, which serves as a key intermediate for constructing complex molecules with tailored properties. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases, inflammation, and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and photoactive materials for electronic applications.
• Chemical Biology Probes: Useful for constructing molecular probes and tags to study biological processes and enzyme functions.
• Custom Synthesis and Scale-Up: Supplied for contract research organizations (CROs) and chemical companies engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	4-Bromo-2-hydroxythiazole
CAS No.	1086381-71-6
Molecular Formula	C3H2BrNOS
Molecular Weight	179.02 g/mol
Synonyms	4-Bromo-1,3-thiazol-2-ol; 2-Hydroxy-4-bromothiazole; 4-Bromo-2-thiazolol; 4-Bromo-2-thiazolin-2-one (tautomer); 4-Bromo-1,3-thiazole-2(3H)-one; 4-Bromothiazol-2-ol; 2(3H)-Thiazolone, 4-bromo-
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2-hydroxythiazole is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support regulatory documentation requirements for global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.