Description

4-Cyclopropyl-1,3-thiazole-2-carboxylic acid is a high-value heterocyclic building block featuring a cyclopropyl-substituted thiazole core with a carboxylic acid functional group. This compound is essential for medicinal chemistry research and development, serving as a key precursor for synthesizing novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical companies, and fine chemical manufacturers seeking to develop new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of novel drug candidates, particularly in areas targeting infectious diseases, oncology, and central nervous system (CNS) disorders.
• Agrochemical Research: Used as a building block in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Ligand and Catalyst Development: The carboxylic acid group allows for derivatization into amides and esters, useful in creating specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials and functional polymers.

Basic Information

Product Name	4-Cyclopropyl-1,3-thiazole-2-carboxylic Acid
CAS No.	1083274-67-2
Molecular Formula	C7H7NO2S
Molecular Weight	169.20 g/mol
Synonyms	2-Cyclopropyl-1,3-thiazole-4-carboxylic Acid; 4-Cyclopropylthiazole-2-carboxylic Acid; 2-Carboxy-4-cyclopropylthiazole; 4-Cyclopropyl-1,3-thiazole-2-carboxylic acid; 1083274-67-2; 4-Cyclopropyl-thiazole-2-carboxylic acid; 4-Cyclopropyl-2-thiazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Cyclopropyl-1,3-thiazole-2-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.