Description

3-Iodo-1H-Pyrrolo[3,2-B]Pyridine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused pyrrolopyridine ring system, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key precursor in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form new carbon-carbon bonds.
• Chemical Biology: Used as a molecular probe or tag in bioconjugation and labeling studies due to its reactive halogen.
• Academic & Contract Research: Employed in universities and CROs for methodological development and exploratory synthesis projects.

Basic Information

Product Name	3-Iodo-1H-Pyrrolo[3,2-B]Pyridine
CAS No.	1083181-26-3
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	3-Iodo-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 3-iodo-; 3-Iodo-7-azaindole; 3-Iodo-1H-7-azaindole; 3-Iodopyrrolo[3,2-b]pyridine; 3-Iodo-1H-pyrrolo[3,2-b]pyridine; 1083181-26-3; 3-Iodo-7-aza-indole
EINECS	Contact for details

Quality Control

Our 3-Iodo-1H-Pyrrolo[3,2-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for advanced intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.