Description

2-Methoxy-3-Methylpyridine-5-Boronicacid is a high-value, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its primary commercial value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and oncology.
• Agrochemical Synthesis: Used to construct novel herbicide and fungicide candidates with improved efficacy and environmental profiles.
• Material Science: Building block for creating organic electronic materials, such as ligands for OLEDs and charge-transport materials.
• Chemical Research: Essential reagent in medicinal chemistry and process R&D for library synthesis and structure-activity relationship (SAR) studies.
• Ligand Synthesis: Intermediate for the preparation of sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Methoxy-3-Methylpyridine-5-Boronicacid
CAS No.	1083168-99-3
Molecular Formula	C8H12BNO3
Molecular Weight	181.00 g/mol
Synonyms	(2-Methoxy-3-methylpyridin-5-yl)boronic acid; 5-Borono-2-methoxy-3-methylpyridine; 3-Methyl-2-methoxypyridine-5-boronic acid; 2-Methoxy-3-methyl-5-pyridineboronic acid; 1083168-99-3; 2-Methoxy-3-methylpyridin-5-ylboronic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxy-3-methylpyridine (pinacol ester precursor)
EINECS	Contact for details

Quality Control

Our 2-Methoxy-3-Methylpyridine-5-Boronicacid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for sensitive coupling reactions. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.