Description

10-Fluoro-2,3,4,6,7,11B-Hexahydro-1H-Pyrazino[2,1-A]Isoquinoline is a high-purity, advanced pharmaceutical intermediate featuring a complex fused-ring structure with a strategic fluorine substitution. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Preclinical Development: Serves as a critical raw material for producing batches of experimental APIs for pharmacological and toxicological testing.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying enzyme function and receptor interactions in biological systems.
• Academic Research: Employed in university and institutional labs for cutting-edge organic synthesis and heterocyclic chemistry projects.

Basic Information

Product Name	10-Fluoro-2,3,4,6,7,11B-Hexahydro-1H-Pyrazino[2,1-A]Isoquinoline
CAS No.	1082914-72-4
Molecular Formula	C₁₃H₁₅FN₂
Molecular Weight	218.27 g/mol
Synonyms	10-Fluoro-1,2,3,4,6,7-hexahydro-11bH-pyrazino[2,1-a]isoquinoline; 10-Fluorohexahydropyrazinoisoquinoline; 1082914-72-4; Pyrazino[2,1-a]isoquinoline, 10-fluoro-2,3,4,6,7,11b-hexahydro-1H-; 1H-Pyrazino[2,1-a]isoquinoline, 10-fluoro-2,3,4,6,7,11b-hexahydro-
EINECS	Contact for details

Quality Control

Our 10-Fluoro-2,3,4,6,7,11B-Hexahydro-1H-Pyrazino[2,1-A]Isoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.