Description

1,2,3,4-Tetrahydroisoquinolin-5-Amine Hydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel bioactive molecules. It is essential for research and production in medicinal chemistry, particularly for targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) and cardiovascular drugs.
• Medicinal Chemistry Research: A fundamental scaffold for designing and optimizing new drug candidates in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Used in the construction of complex heterocyclic compounds, including alkaloids and other nitrogen-containing structures.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its tetrahydroisoquinoline core structure.
• Agrochemical Development: Potential intermediate for creating novel crop protection agents and pesticides.
• Academic & Industrial R&D: Serves as a standard reagent in chemical libraries for discovery programs in both academic institutions and corporate R&D facilities.

Basic Information

Product Name	1,2,3,4-Tetrahydroisoquinolin-5-Amine Hydrochloride
CAS No.	1082658-92-1
Molecular Formula	C9H13ClN2
Molecular Weight	184.67 g/mol
Synonyms	5-Amino-1,2,3,4-tetrahydroisoquinoline hydrochloride; 1,2,3,4-Tetrahydro-5-isoquinolinamine hydrochloride; 5-Aminotetrahydroisoquinoline HCl; THIQ-5-Amine HCl; 1,2,3,4-Tetrahydroisoquinolin-5-ylamine hydrochloride; 5-Amino-THIQ hydrochloride; 5-ATIQ HCl
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydroisoquinolin-5-Amine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and related substances is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.