Description

8-Methyl-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for the synthesis of complex molecules, offering a key structural motif for medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its heterocyclic structure.
• Fine Chemical Production: Employed as a building block for synthesizing specialty chemicals, dyes, and functional materials.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for organic synthesis methodology development and chemical biology studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.

Basic Information

Product Name	8-Methyl-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	1082041-79-9
Molecular Formula	C10H11NO
Molecular Weight	161.20 g/mol
Synonyms	8-Methyl-1,2,3,4-tetrahydroisoquinolin-1-one; 8-Methyl-3,4-dihydro-1(2H)-isoquinolinone; 8-Methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline; 1(2H)-Isoquinolinone, 3,4-dihydro-8-methyl-; 8-Methyl-1,2,3,4-tetrahydroisoquinoline-1-one
EINECS	Contact for details

Quality Control

Our 8-Methyl-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.