Description

1H-Indole-4-Carboxylic Acid, 6-Nitro-, Methyl Ester is a specialized nitro-substituted indole derivative, serving as a high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole scaffold's bioactivity.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, including reduction of the nitro group or hydrolysis of the ester, to access a library of related indole derivatives.
• Material Science: Investigated as a monomer or dopant in the creation of advanced organic electronic materials due to its conjugated indole structure.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) focused on heterocyclic chemistry.

Basic Information

Product Name	1H-Indole-4-Carboxylic Acid, 6-Nitro-, Methyl Ester
CAS No.	1082040-42-3
Molecular Formula	C10H8N2O4
Molecular Weight	220.18 g/mol
Synonyms	Methyl 6-nitro-1H-indole-4-carboxylate; 6-Nitro-1H-indole-4-carboxylic acid methyl ester; 1H-Indole-4-carboxylic acid, 6-nitro-, methyl ester; Methyl 6-nitroindole-4-carboxylate; 6-Nitroindole-4-carboxylic acid methyl ester; 4-(Methoxycarbonyl)-6-nitro-1H-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole-4-Carboxylic Acid, 6-Nitro-, Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Melting Point	Contact for details
Water Content (KF)	< 1.0%
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.