Description

1-[4-(1H-Indol-2-Ylcarbonyl)Piperazin-1-Yl]-2-(Pyrrolidin-1-Yl)Ethane-1,2-Dione is a sophisticated heterocyclic compound featuring a piperazine linker and indole moiety, designed for advanced research and development. This high-purity chemical building block is critical for medicinal chemistry programs, enabling the synthesis of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, particularly those targeting specific enzyme or receptor pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
• Biochemical Tool Compound: Employed in biochemical assays and pharmacological studies to investigate biological mechanisms and validate new therapeutic targets.
• Fine Chemical Synthesis: Acts as a specialized building block for the custom synthesis of complex, high-value organic molecules for advanced applications.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory research in organic and bioorganic chemistry.

Basic Information

Item	Details
Product Name	1-[4-(1H-Indol-2-Ylcarbonyl)Piperazin-1-Yl]-2-(Pyrrolidin-1-Yl)Ethane-1,2-Dione
CAS No.	1081143-31-8
Molecular Formula	C20H22N4O3
Molecular Weight	366.42 g/mol
Synonyms	1-[4-(1H-Indol-2-ylcarbonyl)piperazin-1-yl]-2-(pyrrolidin-1-yl)ethane-1,2-dione; 1-[4-(1H-Indole-2-carbonyl)piperazin-1-yl]-2-(pyrrolidin-1-yl)ethane-1,2-dione; 1081143-31-8; 2-(1H-Indole-2-carbonyl)-N-[2-(pyrrolidin-1-yl)-2-oxoacetyl]piperazine-1-carboxamide (related structure); Indole-piperazine-pyrrolidine trione derivative
EINECS	Contact for details

Quality Control

Our production of 1-[4-(1H-Indol-2-Ylcarbonyl)Piperazin-1-Yl]-2-(Pyrrolidin-1-Yl)Ethane-1,2-Dione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical research, with specifications that can align with GMP-grade requirements for non-clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and/or hygroscopic; handling under an inert atmosphere is recommended for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.