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(1-Methyl-1H-Indol-2-Yl)[4-(Thiophen-2-Ylsulfonyl)Piperazin-1-Yl]Methanone CAS NO 1081128-65-5


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CAS No.:1081128-65-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1-Methyl-1H-Indol-2-Yl)[4-(Thiophen-2-Ylsulfonyl)Piperazin-1-Yl]Methanone is a high-value, complex heterocyclic compound designed for advanced research and development. This molecule is significant as a key synthetic intermediate or potential pharmacophore in the discovery of novel bioactive compounds. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas like kinase inhibition or central nervous system (CNS) targeting.

Application

  • Pharmaceutical Research & Development: Serves as a critical building block or lead compound in the synthesis of novel drug candidates for preclinical studies.
  • Kinase Inhibitor Development: Its structural motifs make it a valuable scaffold for designing and screening potential kinase inhibitors.
  • Chemical Biology Probes: Used in the development of molecular probes to study specific biological pathways and protein functions.
  • Fine Chemical Synthesis: Acts as a sophisticated intermediate in multi-step organic syntheses for complex, high-value specialty chemicals.
  • Contract Research Organizations (CROs): Supplied to CROs conducting custom synthesis and medicinal chemistry services for client projects.
  • Academic Research: Utilized in university and institutional labs for fundamental research in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name (1-Methyl-1H-Indol-2-Yl)[4-(Thiophen-2-Ylsulfonyl)Piperazin-1-Yl]Methanone
CAS No. 1081128-65-5
Molecular Formula C18H19N3O3S2
Molecular Weight 389.49 g/mol
Synonyms 1-(1-Methyl-1H-indole-2-carbonyl)-4-(thiophen-2-ylsulfonyl)piperazine; 4-(Thiophene-2-sulfonyl)-1-[(1-methyl-1H-indol-2-yl)carbonyl]piperazine; (1-Methylindol-2-yl)[4-(thiophen-2-ylsulfonyl)piperazin-1-yl]methanone; Methanone, (1-methyl-1H-indol-2-yl)[4-(2-thienylsulfonyl)-1-piperazinyl]-; 1081128-65-5; (1-Methyl-1H-indol-2-yl)-[4-(thiophene-2-sulfonyl)piperazin-1-yl]methanone
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Quality Control

Our (1-Methyl-1H-Indol-2-Yl)[4-(Thiophen-2-Ylsulfonyl)Piperazin-1-Yl]Methanone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant standards for research chemicals, and custom synthesis and purification to specific specifications (e.g., >95%, >98%, >99% HPLC purity) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95% (Higher grades available)
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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