Description

1-[4-(1H-Indol-2-Ylcarbonyl)Piperazin-1-Yl]-5-(Piperidin-1-Yl)Pentane-1,5-Dione is a sophisticated heterocyclic compound featuring a unique molecular architecture that combines indole, piperazine, and piperidine pharmacophores. This structure makes it a valuable advanced pharmaceutical intermediate or research chemical for the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D organizations and contract research and manufacturing services (CRAMS) engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, or other therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities.
• Biochemical Tool Compound: May be employed in vitro to study enzyme inhibition or receptor binding activities related to its structural motifs.
• Contract Manufacturing: Supplied to CDMOs for scale-up and cGMP production of active pharmaceutical ingredients (APIs) under development.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and pharmacological investigations.

Basic Information

Product Name	1-[4-(1H-Indol-2-Ylcarbonyl)Piperazin-1-Yl]-5-(Piperidin-1-Yl)Pentane-1,5-Dione
CAS No.	1081117-67-0
Molecular Formula	C27H34N4O3
Molecular Weight	462.59 g/mol
Synonyms	1-[4-(1H-Indol-2-carbonyl)piperazin-1-yl]-5-(piperidin-1-yl)pentane-1,5-dione; 1,5-Pentanedione, 1-[4-(1H-indol-2-ylcarbonyl)-1-piperazinyl]-5-(1-piperidinyl)-; 1081117-67-0; UNII-9J0Q6KQ8QN; 9J0Q6KQ8QN; AKOS025310999; 1-(4-(1H-indole-2-carbonyl)piperazin-1-yl)-5-(piperidin-1-yl)pentane-1,5-dione
EINECS	Contact for details

Quality Control

Our production of 1-[4-(1H-Indol-2-Ylcarbonyl)Piperazin-1-Yl]-5-(Piperidin-1-Yl)Pentane-1,5-Dione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.