Description

1-(4-Acetylpiperazin-1-Yl)-2-(2-Phenyl-1H-Indol-1-Yl)Ethanone is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is valued for its complex heterocyclic structure, which serves as a critical building block for synthesizing novel bioactive molecules. It is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Kinase Inhibitor Research: Used in the development and screening of potential kinase inhibitors for cancer therapy.
• CNS Drug Discovery: Serves as a scaffold for compounds being investigated for neurological and psychiatric disorders.
• Chemical Biology Probes: Employed in the creation of molecular probes to study protein function and cellular signaling mechanisms.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial production of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for fundamental medicinal chemistry research.

Basic Information

Product Name	1-(4-Acetylpiperazin-1-Yl)-2-(2-Phenyl-1H-Indol-1-Yl)Ethanone
CAS No.	1081113-28-1
Molecular Formula	C22H21N3O2
Molecular Weight	359.43 g/mol
Synonyms	1-[2-(2-Phenyl-1H-indol-1-yl)acetyl]-4-acetylpiperazine; 2-(2-Phenyl-1H-indol-1-yl)-1-(4-acetyl-1-piperazinyl)ethanone; 1-(4-Acetylpiperazin-1-yl)-2-(2-phenylindol-1-yl)ethanone; 1081113-28-1; AKOS025310991; 1-(4-acetylpiperazin-1-yl)-2-(2-phenyl-1H-indol-1-yl)ethan-1-one; 1-(4-Acetylpiperazin-1-yl)-2-(2-phenyl-1H-indol-1-yl)ethanone; 1-(4-Acetyl-1-piperazinyl)-2-(2-phenyl-1H-indol-1-yl)ethanone
EINECS	Contact for details

Quality Control

Our 1-(4-Acetylpiperazin-1-Yl)-2-(2-Phenyl-1H-Indol-1-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply of this high-value intermediate for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.