Description

Ethyl 1-Bromoisoquinoline-3-Carboxylate is a high-purity brominated isoquinoline derivative serving as a versatile and critical building block in advanced organic synthesis. This compound is valued for its reactive bromine substituent and ester functionality, enabling precise molecular construction for complex target molecules. It is primarily required by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for the synthesis of novel heterocyclic compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing the isoquinoline scaffold.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new therapeutic agents targeting various diseases.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce complex fragments.
• Agrochemical Research: Serves as an intermediate in the development of new pesticides and herbicides.
• Material Science: Potential monomer or precursor for the synthesis of specialized organic electronic materials or ligands for catalysts.

Basic Information

Product Name	Ethyl 1-Bromoisoquinoline-3-Carboxylate
CAS No.	1079947-40-2
Molecular Formula	C₁₂H₁₀BrNO₂
Molecular Weight	280.12 g/mol
Synonyms	1-Bromoisoquinoline-3-carboxylic acid ethyl ester; Ethyl 1-bromo-3-isoquinolinecarboxylate; 3-Carbethoxy-1-bromoisoquinoline; 1-Bromo-3-ethoxycarbonylisoquinoline; Ethyl 1-bromoisoquinoline-3-carboxylate; 1-Bromoisoquinoline-3-carboxylic Acid Ethyl Ester; Isoquinoline-3-carboxylic acid, 1-bromo-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-Bromoisoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques such as HPLC, NMR, and mass spectrometry. Our quality commitment ensures material integrity for your sensitive research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.