Description

2-Phthalimidyl-3-(3Hydroxyphenyl)Propionic Acid Methyl Ester is a specialized organic compound featuring a phthalimide-protected amine group and a phenolic ester moiety. This unique bifunctional structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for synthetic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of complex target molecules, including potential active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly those targeting neurological or inflammatory pathways.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics due to its protected amine functionality.
• Protecting Group Chemistry: Serves as a reagent where the phthalimidyl group acts as a protective group for amines in complex organic syntheses.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis or metal-organic frameworks.
• Academic & Industrial R&D: A critical material for methodological development in organic synthesis and medicinal chemistry research programs.
• Fine Chemical Production: Used in the manufacture of high-value, low-volume specialty chemicals with specific chiral or functional properties.

Basic Information

Product Name	2-Phthalimidyl-3-(3Hydroxyphenyl)Propionic Acid Methyl Ester
CAS No.	1076199-35-3
Molecular Formula	C20H17NO5
Molecular Weight	351.36 g/mol
Synonyms	Methyl 2-phthalimido-3-(3-hydroxyphenyl)propanoate; Methyl 3-(3-hydroxyphenyl)-2-(1,3-dioxoisoindolin-2-yl)propanoate; 2-(1,3-Dioxoisoindolin-2-yl)-3-(3-hydroxyphenyl)propanoic acid methyl ester; 3-(3-Hydroxyphenyl)-2-phthalimidopropionic acid methyl ester; N-Phthaloyl-3-(3-hydroxyphenyl)-D,L-alanine methyl ester; Phthalimide-protected tyrosine derivative methyl ester
EINECS	Contact for details

Quality Control

Our 2-Phthalimidyl-3-(3Hydroxyphenyl)Propionic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliable integration into your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.