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11-Maleimidoundecane-1-Carbonyl-1-(T-Butyl)Carbazate CAS NO 1076198-39-4


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CAS No.:1076198-39-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

11-Maleimidoundecane-1-Carbonyl-1-(T-Butyl)Carbazate is a specialized heterobifunctional crosslinking agent designed for advanced bioconjugation. This compound is critical for creating stable, site-specific linkages between biomolecules and surfaces or other functional molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostics, and life sciences sectors for developing targeted therapeutics, immunoassays, and biosensors.

Application

  • Antibody-Drug Conjugate (ADC) Development: Site-specific conjugation of cytotoxic payloads to monoclonal antibodies via thiol-maleimide chemistry.
  • Protein and Peptide Labeling: Introduction of stable, cleavable linkers or tags for tracking, purification, or functionalization.
  • Surface Immobilization: Functionalization of biosensor chips, microarray slides, or nanoparticle surfaces with biomolecules for capture assays.
  • Polymer Modification: Synthesis of functionalized polymers or hydrogels for controlled drug delivery systems.
  • Diagnostic Reagent Synthesis: Production of enzyme-linked or fluorescently labeled antibodies and antigens for immunoassays.
  • Biomaterial Engineering: Creating bioactive scaffolds for tissue engineering by covalently attaching growth factors or cell-adhesion peptides.

Basic Information

Product Name 11-Maleimidoundecane-1-Carbonyl-1-(T-Butyl)Carbazate
CAS No. 1076198-39-4
Molecular Formula C19H31N3O5
Molecular Weight 381.47 g/mol
Synonyms 1-(11-Maleimidoundecanoyl)-2-(tert-butyl)hydrazine; tert-Butyl 11-maleimidoundecanoic hydrazide; Maleimide-PEG11-t-Boc-hydrazide; Boc-hydrazide-PEG11-maleimide; Heterobifunctional PEG Crosslinker (Maleimide, Boc-Hydrazide); 2-(tert-Butyl)-1-(11-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoyl)hydrazine; N-(tert-Butoxycarbonyl)-N'-[11-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)undecanoyl]hydrazine
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Quality Control

Our 11-Maleimidoundecane-1-Carbonyl-1-(T-Butyl)Carbazate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and cGMP applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and custom purity grades or analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 1.0%
Solubility Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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