Description

Ethyl 7-Bromo-3-(3-Ethoxy-3-Oxopropyl)-1H-Indole-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex indole-based structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Used in the development of new generation herbicides and plant growth regulators with specific biological activity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce functionalized indole moieties into target molecules.
• Bioconjugate Chemistry: Potential use in creating labeled probes or antibody-drug conjugates (ADCs) for diagnostic or therapeutic applications.
• Academic & Institutional Research: Utilized in university and government labs for fundamental studies in heterocyclic chemistry and reaction methodology development.

Basic Information

Product Name	Ethyl 7-Bromo-3-(3-Ethoxy-3-Oxopropyl)-1H-Indole-2-Carboxylate
CAS No.	1073493-75-0
Molecular Formula	C₁₆H₁₈BrNO₄
Molecular Weight	368.22 g/mol
Synonyms	7-Bromo-3-(3-ethoxy-3-oxopropyl)-1H-indole-2-carboxylic acid ethyl ester; Ethyl 7-bromo-3-[2-(ethoxycarbonyl)ethyl]-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 7-bromo-3-(3-ethoxy-3-oxopropyl)-, ethyl ester; 7-Bromo-3-(2-carbethoxyethyl)indole-2-carboxylic acid ethyl ester; 2-Carbethoxy-7-bromo-3-(2-carbethoxyethyl)indole
EINECS	Contact for details

Quality Control

Our Ethyl 7-Bromo-3-(3-Ethoxy-3-Oxopropyl)-1H-Indole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.