Description

2-Bromo-5-(4-Fluorophenyl)Thiophene is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile reactivity, serving as a key intermediate for constructing complex molecular architectures in pharmaceutical and materials science research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and fluorophenyl motifs.
• Material Science: Serves as a building block for organic semiconductors, conductive polymers, and non-linear optical (NLO) materials due to its electron-rich thiophene core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, including palladium-catalyzed cross-coupling reactions like Suzuki and Stille couplings.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent tags and molecular probes for imaging and diagnostic applications.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-Bromo-5-(4-Fluorophenyl)Thiophene
CAS No.	1073313-97-9
Molecular Formula	C10H6BrFS
Molecular Weight	257.12 g/mol
Synonyms	2-Bromo-5-(4-fluorophenyl)thiophene; 5-(4-Fluorophenyl)-2-bromothiophene; 2-Bromo-5-(p-fluorophenyl)thiophene; Thiophene, 2-bromo-5-(4-fluorophenyl)-; 1073313-97-9; 2-Bromo-5-(4'-fluorophenyl)thiophene; 4-(2-Bromothiophen-5-yl)fluorobenzene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-(4-Fluorophenyl)Thiophene is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. Certificates of Analysis (COA) documenting batch-specific results are provided with each shipment and are available upon request. We support custom synthesis to meet specific purity requirements (e.g., ≥98%, ≥99%) for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.