Description

5-(5-Borono-1H-Indol-1-Yl)Pentanoic Acid is a specialized boron-containing indole derivative, serving as a valuable synthetic intermediate and building block in modern organic chemistry. Its core value lies in the unique reactivity of the boronic acid functional group, which enables critical carbon-carbon bond-forming reactions, particularly in cross-coupling methodologies. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Suzuki-Miyaura Cross-Coupling Reagent: Utilized as a critical partner in palladium-catalyzed cross-coupling reactions to construct biaryl and heterobiaryl systems, a cornerstone of modern medicinal chemistry.
• Agrochemical Research: Employed in the discovery and development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Used in the synthesis of organic electronic materials, such as those for OLEDs (Organic Light-Emitting Diodes) and sensors, where the indole-boronic acid motif can impart specific electronic properties.
• Chemical Biology Probe Development: Serves as a versatile handle for bioconjugation and the creation of activity-based probes to study enzyme function and protein interactions.
• Academic & Contract Research: A fundamental reagent for methodology development and complex natural product synthesis in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	5-(5-Borono-1H-Indol-1-Yl)Pentanoic Acid
CAS No.	1072946-60-1
Molecular Formula	C₁₃H₁₆BNO₄
Molecular Weight	261.08 g/mol
Synonyms	5-(5-Boron-1H-indol-1-yl)pentanoic acid; 1-(4-Carboxybutyl)-1H-indole-5-boronic acid; 5-(5-Boronindol-1-yl)valeric acid; 5-(1H-Indol-5-ylboronic acid)pentanoic acid; 5-(5-Boronoindol-1-yl)pentanoic acid; 5-(Indol-5-ylboronic acid)pentanoic acid; Valeric acid, 5-(5-borono-1H-indol-1-yl)-
EINECS	Contact for details

Quality Control

Our 5-(5-Borono-1H-Indol-1-Yl)Pentanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed results from techniques including HPLC, NMR, and elemental analysis. Our quality commitment supports compliance with the standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Allow the sealed container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.