Description

2-Chloro-5-Methoxypyridine-3-Boronic Acid is a versatile and high-value boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced pyridine-based herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Employed in the development of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Research: Serves as a fundamental reagent in academic and industrial R&D for exploring new heterocyclic compounds and catalytic processes.
• Ligand Synthesis: Useful for preparing specialized boronate ligands used in catalysis and molecular recognition applications.

Basic Information

Product Name	2-Chloro-5-Methoxypyridine-3-Boronic Acid
CAS No.	1072946-26-9
Molecular Formula	C6H7BClNO3
Molecular Weight	187.39 g/mol
Synonyms	(2-Chloro-5-methoxypyridin-3-yl)boronic acid; 3-Borono-2-chloro-5-methoxypyridine; 2-Chloro-5-methoxy-3-pyridineboronic acid; 2-Chloro-5-methoxypyridine-3-boronic acid pinacol ester (common derivative); 1072946-26-9; 2-Chloro-5-methoxy-3-pyridinylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-Methoxypyridine-3-Boronic Acid is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC and NMR, to ensure high purity and consistency for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.