Description

2-(Methylsulfanyl)Pyridine-3-Boronic Acid is a versatile organoboron building block, specifically a pyridine-substituted boronic acid derivative. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures in medicinal chemistry and materials science. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyridine-thioether motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science: Serves as a precursor for creating organic electronic materials, such as ligands for catalysts or components in organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Can be utilized in the development of molecular probes and bioconjugation reagents due to its reactive boronic acid group.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds with aryl or vinyl halides.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	2-(Methylsulfanyl)Pyridine-3-Boronic Acid
CAS No.	1072944-21-8
Molecular Formula	C6H8BNO2S
Molecular Weight	169.01 g/mol
Synonyms	(3-Pyridinylboronic acid, 2-(methylthio)-); 2-(Methylthio)pyridine-3-boronic acid; 2-(Methylsulfanyl)-3-pyridineboronic acid; 3-Borono-2-(methylthio)pyridine; 2-Methylsulfanylpyridine-3-boronic acid; 2-(Methylmercapto)pyridine-3-boronic acid; Pyridine-3-boronic acid, 2-(methylthio)-
EINECS	Contact for details

Quality Control

Our 2-(Methylsulfanyl)Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation upon opening.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.