Description

n-(1H-Indol-2-Ylcarbonyl)-L-Valine is a specialized, high-purity chemical building block designed for advanced research and development. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical sector where precise molecular architecture is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel therapeutic candidates and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways.
• Peptidomimetic Research: Used in the design and development of peptidomimetics and constrained peptides due to its valine backbone and indole carbonyl moiety.
• Protease Inhibitor Development: Serves as a core structure or precursor in the research of enzyme inhibitors, including protease and kinase inhibitors.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying protein-protein interactions and cellular signaling pathways.
• Combinatorial Chemistry: A valuable scaffold in solid-phase and solution-phase library synthesis for drug discovery screening.
• Academic & Institutional Research: Used in universities and research institutes for fundamental studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	n-(1H-Indol-2-Ylcarbonyl)-L-Valine
CAS No.	1072856-64-4
Molecular Formula	C15H16N2O3
Molecular Weight	272.30 g/mol
Synonyms	L-Valine, N-[(1H-indol-2-yl)carbonyl]-; N-(1H-Indole-2-carbonyl)-L-valine; (S)-2-((1H-Indole-2-carboxamido)-3-methylbutanoic acid; Valine, N-(1H-indol-2-ylcarbonyl)-, L-; 2-(1H-Indole-2-carboxamido)-3-methylbutanoic acid; UNII-2V3G2Z3Q0G; 2V3G2Z3Q0G; SCHEMBL218284
EINECS	Contact for details

Quality Control

Our n-(1H-Indol-2-Ylcarbonyl)-L-Valine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.