Description

3-Nitro-4-Phenoxy-5-Sulfamoylbenzoic Acid-D5 is a deuterated derivative of a key benzoic acid-based compound, serving as a critical internal standard and reference material in analytical chemistry. Its primary value lies in enabling precise quantification and metabolic pathway tracing in complex biological matrices through advanced mass spectrometry techniques. This high-purity material is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and contract research organization (CRO) sectors.

Application

• Internal Standard for LC-MS/MS: Used as a stable isotope-labeled internal standard for the accurate quantification of its non-deuterated counterpart in bioanalytical method development and validation.
• Metabolite Studies: Facilitates the study of drug metabolism and pharmacokinetics (DMPK) by tracing metabolic pathways and identifying metabolites in preclinical and clinical research.
• Pharmaceutical Impurity Profiling: Acts as a reference standard in the identification and control of process-related impurities and degradation products during active pharmaceutical ingredient (API) development.
• Environmental and Residue Analysis: Employed in sophisticated analytical methods for detecting trace levels of related compounds in environmental samples or food safety testing.
• Chemical Synthesis Research: Serves as a specialized building block or tracer in the synthesis of novel deuterated compounds for research purposes.

Basic Information

Product Name	3-Nitro-4-Phenoxy-5-Sulfamoylbenzoic Acid-D5
CAS No.	1072125-53-1
Molecular Formula	C13H4D5N2O7S
Molecular Weight	~332.30 g/mol
Synonyms	Benzoic acid, 3-nitro-4-phenoxy-5-sulfamoyl-, pentadeuterio-; 3-Nitro-4-phenoxy-5-sulfamoylbenzoic-d5 acid; 5-Sulfamoyl-3-nitro-4-phenoxybenzoic Acid-D5; Deuterated Furosemide Impurity/Intermediate; [D5]-3-Nitro-4-phenoxy-5-sulfamoylbenzoic Acid; Furosemide-d5 Related Compound; 4-Phenoxy-3-nitro-5-sulfamoylbenzoic Acid-D5
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-Phenoxy-5-Sulfamoylbenzoic Acid-D5 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment suitable for use as a reference material. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic purity (D-content), and identity confirmation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.