Description

1-Isopropyl-1H-Pyrazole-4-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and the development of advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, particularly in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs) and candidate drug molecules.
• Agrochemical Synthesis: Employed in the creation of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science Research: Acts as a precursor for organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Probe Development: Utilized for bioconjugation and the synthesis of molecular probes for biological target identification.
• Library Synthesis for High-Throughput Screening: Facilitates the rapid generation of diverse compound libraries in drug discovery programs.

Basic Information

Product Name	1-Isopropyl-1H-Pyrazole-4-Boronic Acid, Pinacol Ester
CAS No.	1071496-88-2
Molecular Formula	C12H21BN2O2
Molecular Weight	236.12 g/mol
Synonyms	1-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1H-Pyrazole-4-boronic acid, 1-(1-methylethyl)-, pinacol ester; 1-Isopropyl-1H-pyrazole-4-boronic acid pinacol ester; 1-Isopropyl-4-(pinacolboryl)-1H-pyrazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isopropyl-1H-pyrazole; 1-Isopropylpyrazole-4-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-1H-Pyrazole-4-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.