Description

2-Thiazolamine, 5-(5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This heterocyclic compound is of significant commercial interest due to its role as a key building block in medicinal chemistry, particularly for the development of kinase inhibitors and other targeted therapies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of innovative drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new chemical entities in drug discovery programs.
• Biochemical Tool Compound: Used in biochemical assays and as a reference standard to study biological pathways and protein interactions in academic and industrial research settings.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.
• Agrochemical Research: Potential application as an intermediate in the development of novel agrochemicals, leveraging its heterocyclic structure.

Basic Information

Product Name	2-Thiazolamine, 5-(5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)-
CAS No.	1071455-03-2
Molecular Formula	C10H7BrN4S
Molecular Weight	295.16 g/mol
Synonyms	5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)thiazol-2-amine; 5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-1,3-thiazol-2-amine; 5-(5-Bromo-7-azaindol-3-yl)thiazol-2-amine; 5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-thiazolamine; 5-(5-Bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)thiazole-2-amine; 5-(5-Bromo-7-azaindol-3-yl)-2-aminothiazole
EINECS	Contact for details

Quality Control

Our 2-Thiazolamine, 5-(5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use and can supply material produced under cGMP guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.