Description

1-[4-(3-Chloropropoxy)-3-Methoxyphenyl]Ethanone-D3 is a deuterated aromatic ketone derivative, serving as a critical stable isotope-labeled intermediate in advanced chemical synthesis. This compound is essential for researchers and manufacturers requiring high-purity, isotopically labeled building blocks to develop novel compounds with enhanced metabolic stability and traceability. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of deuterated active pharmaceutical ingredients (APIs) and for use in mass spectrometry as an internal standard.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing deuterated drug candidates, leveraging the kinetic isotope effect for improved metabolic stability and pharmacokinetic profiles.
• Agrochemical Research: Used in the development of novel, isotopically labeled pesticides and herbicides for metabolic and environmental fate studies.
• Analytical Reference Standard: Serves as a high-purity internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification in complex matrices.
• Organic Synthesis: Employed in advanced organic chemistry research for constructing complex molecules where the deuterium label is required for mechanistic studies or structural elucidation.
• Material Science: Potential precursor for synthesizing specialty polymers or liquid crystals with unique properties derived from deuterium incorporation.

Basic Information

Product Name	1-[4-(3-Chloropropoxy)-3-Methoxyphenyl]Ethanone-D3
CAS No.	1071167-68-4
Molecular Formula	C₁₂H₁₂D₃ClO₃
Molecular Weight	245.73 g/mol
Synonyms	1-[4-(3-Chloropropoxy)-3-methoxyphenyl]ethanone-d3; 1-[4-(3-Chloropropoxy)-3-methoxyphenyl]ethanone-2,2,2-d3; 3'-Chloropropoxy-4'-methoxydeuterioacetophenone; Deuterated 1-(4-(3-Chloropropoxy)-3-methoxyphenyl)ethanone; 2,2,2-Trideuterio-1-[4-(3-chloropropoxy)-3-methoxyphenyl]ethanone; 1-(4-(3-Chloropropoxy)-3-methoxyphenyl)ethanone-α,α,α-d3; Acetophenone-d3, 4'-(3-chloropropoxy)-3'-methoxy-
EINECS	Contact for details

Quality Control

Our 1-[4-(3-Chloropropoxy)-3-Methoxyphenyl]Ethanone-D3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C), HPLC, and mass spectrometry, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.