Description

tert-Butyl(Chroman-4-Yloxy)Dimethylsilane is a specialized organosilicon compound used as a key intermediate in advanced organic synthesis. Its value lies in its role as a versatile protecting group for alcohols, particularly in the multi-step synthesis of complex pharmaceutical molecules and fine chemicals. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity building blocks for constructing intricate molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for protecting hydroxyl groups during complex reaction sequences.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances.
• Material Science Research: Employed in the development of novel silicon-based polymers and advanced organic materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process optimization studies.
• Peptide Synthesis: Can be utilized for the protection of serine, threonine, or tyrosine side chains in solid-phase peptide synthesis.

Basic Information

Product Name	tert-Butyl(Chroman-4-Yloxy)Dimethylsilane
CAS No.	1065075-49-1
Molecular Formula	C15H24O2Si
Molecular Weight	264.44 g/mol
Synonyms	tert-Butyl(chroman-4-yloxy)dimethylsilane; 4-[(tert-Butyldimethylsilyl)oxy]chroman; Chroman-4-yloxy-tert-butyldimethylsilane; TBDMS Chroman-4-yl Ether; tert-Butyldimethyl(chroman-4-yloxy)silane; 4-(tert-Butyldimethylsilyloxy)chroman; Chroman-4-ol, tert-butyldimethylsilyl ether
EINECS	Contact for details

Quality Control

Our tert-Butyl(Chroman-4-Yloxy)Dimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.