Description

4-Chloro-Benzooxazole-2-Thiol is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique scaffold enables the introduction of both chloro and thiol functionalities. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to create novel active compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its bioactive heterocyclic core.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers, ligands, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical reactions.
• Ligand and Catalyst Design: The thiol and chloro groups make it a valuable starting point for synthesizing chelating ligands and organocatalysts.

Basic Information

Product Name	4-Chloro-Benzooxazole-2-Thiol
CAS No.	1062320-24-4
Molecular Formula	C7H4ClNOS
Molecular Weight	185.63 g/mol
Synonyms	4-Chloro-1,3-benzoxazole-2-thiol; 4-Chloro-2-mercaptobenzoxazole; 2-Mercapto-4-chlorobenzoxazole; 4-Chlorobenzo[d]oxazole-2-thiol; 4-Chloro-2-benzoxazolethiol; 4-Chloro-2-sulfanylbenzoxazole; 4-Chloro-2-thiolbenzoxazole; 4-Chloro-2-hydroxybenzoxazole tautomer
EINECS	Contact for details

Quality Control

Our 4-Chloro-Benzooxazole-2-Thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents, supporting compliance with cGMP and other relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.